Opening files, applications, Web documents, and the mail client Opening a file: \\\ Imports System.Diagnostics . . . Dim psi As New ProcessStartInfo() psi.UseShellExecute = True psi.FileName = "C:\bla.html" Process.Start(psi) /// Starting an application: If you want to start an application, you can simply call 'System.Diagnostics.Process.Start("C:\bla.exe")' or in VB.NET 'Shell("C:\bla.exe")'. Opening a webpage in the default browser: For starting the system's default browser with a predefined URL, specify the URL you want to be displayed instead of the filename in the code listed above. The code below can be used to start a new instance of Internet Explorer and display a certain webpage: \\\ Imports System.Diagnostics . . . Dim psi As New ProcessStartInfo() With psi .FileName = "iexplore" .Arguments = "-new http://dotnet.mvps.org/" End With Process.Start(psi) /// The command-line switches for Internet Explorer are documented here: Command line switches for Internet Explorer 4.0 There is an option in Internet Explorer, that, if set, forces new pages to be opened in an existing instance (browser window) of Internet Explorer: Description of the Reuse Windows for Launching Shortcuts Setting in Internet Explorer 5.01 Opening the default mail client with a mail template: Sample based on work by Fergus Cooney and Cor Ligthert [MVP], optimized and extended by Herfried K. Wagner [MVP]: Add a reference to "System.Web.dll". Then you can use this code: \\\ Imports System.Diagnostics Imports System.Web . . . Public Sub StartDefaultMail( _ ByVal [To] As String, _ Optional ByVal Subject As String = "", _ Optional ByVal Message As String = "" _ ) Try Dim psi As New ProcessStartInfo() psi.UseShellExecute = True psi.FileName = _ "mailto:" & HttpUtility.UrlEncode([To]) & _ "?subject=" & HttpUtility.UrlEncode(Subject) & _ "&body=" & HttpUtility.UrlEncode(Message) Process.Start(psi) Catch ex As Exception Throw _ New ApplicationException( _ "Default mail client could not be started.", _ ex _ ) End Try End Sub /// Usage: \\\ StartDefaultMail( _ "foo@goo.baz", _ "Invitation", _ "Do you want to come to my party?" _ ) /// 'mailto' Protocol